Reliving the History of Life using Experimental Evolutionary Genomics
I seek to illuminate the evolution of complex traits that increase biodiversity, control cell lifespan and drive major transitions in the history of life. The specific goals of this research are to understand how changes in genome architecture alter global patterns of gene expression, to elucidate how these changes explain the behavior of novel genotypes, and to investigate how the tempo and trajectory of adaptation is influenced by epistasis, trade-offs and biophysical constraints. Because major evolutionary transitions are driven by cooperation, my group is especially keen to discover the genetic basis of cooperative behaviors. Our approach to these goals is to carry out evolutionary experiments in the laboratory using microbes such as the bacterium Escherichia coli, the Bakers yeast Saccharomyces cerevisiae and the alga, Chlamydomonas reinhardtii. My team and I have published extensively in respected journals such as Proceedings of the National Academy of Sciences (USA), PLoS Genetics, and Nature Communications. My laboratory at Georgia Tech is funded by NIH, NSF, the Templeton Foundation, and NASA. I am a Principal Investigator of the NASA Astrobiology Institute node: “Reliving the Past: Experimental Evolution of Major Transitions.”
Frank Rosenzweig is a Professor of Biology in the College of Sciences at Georgia Institute of Technology. He has previously held tenured faculty positions at the University of Idaho, the University of Florida and the University of Montana, and has been Visiting Professor at Stanford School of Medicine. Rosenzweig received his B.A. in Comparative Literature at the University of Tennessee, and did post-baccalaureate work in Zoology at Duke University. He earned his Ph.D. in Biology at the University of Pennsylvania, and was an NIH postdoctoral fellow at the University of Michigan.